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Can a PDA reopen in adulthood?

After the PDA has been closed, medical follow-up is unnecessary in the absence of other symptoms. However, some physicians recommend periodic monitoring because a PDA that was closed in childhood will occasionally reopen in the adult patient and require treatment.

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Large PDAs are rarely discovered in the adult patient. If present, they are often associated with high pulmonary blood pressures and pulmonary vascular obstructive disease (PVOD), which may be the result of the left to right shunt (the movement of blood from the aorta into the pulmonary artery through the open ductus (PDA)). This shunting may cause enlargement (dilatation) of the left chambers of the heart, resulting in heart palpitations (atrial fibrillation) and/or heart failure. Diagnosis of a small PDA is often difficult because of the lack of major symptoms. However, there will usually be a murmur, though often a mild one, and the patient may experience no symptoms. Symptoms of fatigue and/or shortness of breath in response to exertion is common in patients with larger PDAs. Very small PDAs producing negligible symptoms, called "silent ductus" because of the lack of a distinctive murmur, do not present risks and are usually left untreated. The PDA is best observed and evaluated through echocardiography, producing an echocardiogram, which will allow the physician to study its size and effects. In some cases, a cardiac catheterization procedure will be necessary to confirm the diagnosis. If a significant PDA is found to exist, closure may be necessary in order to stop the left to right shunting of blood. PDAs are also closed in order to guard against infection of the interior lining of the heart (bacterial endocarditis, or BE). A catheterization procedure may be used to close the PDA through the insertion of an occlusion device, such as a coil or Amplatzer. These devices block the flow of blood through the PDA and encourage its anatomic closure. In other cases, the PDA will be surgically tied off (ligated) or separated. If calcification of the PDA in the older patient is significant, other means of surgical closure of the PDA may be necessary. After the PDA has been closed, medical follow-up is unnecessary in the absence of other symptoms. However, some physicians recommend periodic monitoring because a PDA that was closed in childhood will occasionally reopen in the adult patient and require treatment. This becomes less likely as techniques for closure improve. If the closure is not complete and a small leakage of blood through the PDA continues, then antibiotics may be prescribed to guard against infection (bacterial endocarditis).

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At what age is PDA surgery done?

Patent ductus arteriosus repair or closure. Repair is usually indicated in infants younger than 6 months of age who have large defects that are causing symptoms, such as poor weight gain and rapid breathing. For infants who do not exhibit symptoms, the repair may often be delayed until after 6 to 12 months of age.

Pediatric Patent Ductus Arteriosus (PDA)

What is patent ductus arteriosus (PDA)?

PDA is a heart problem that is frequently noted in the first few weeks or months after birth. It is characterized by the persistence of a normal prenatal connection between the aorta and the pulmonary artery which allows oxygen-rich (red) blood that should go to the body to recirculate through the lungs. All babies are born with this connection between the aorta and the pulmonary artery. While your baby was developing in the uterus, it was not necessary for blood to circulate through the lungs because oxygen was provided through the placenta. During pregnancy, a connection was necessary to allow oxygen-rich (red) blood to bypass your baby's lungs and proceed into the body. This normal connection that all babies have is called a ductus arteriosus. At birth, the placenta is removed when the umbilical cord is cut. Your baby's lungs must now provide oxygen to his or her body. As your baby takes the first breath, the blood vessels in the lungs open up, and blood begins to flow through them to pick up oxygen. At this point, the ductus arteriosus is not needed to bypass the lungs. Under normal circumstances, within the first few days after birth, the ductus arteriosus closes and blood no longer passes through it. In some babies, however, the ductus arteriosus remains open (patent) and the condition now becomes known as patent ductus arteriosus (PDA). The opening between the aorta and the pulmonary artery allows oxygen-rich (red) blood to recirculate into the lungs.

Patent ductus arteriosus occurs twice as often in girls as in boys.

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